Michael J. Bumbulis

Dr. Michael J. Bumbulis earned a Master of Science in zoology from The Ohio State University and a doctorate in genetics from Case Western Reserve University. After receiving his undergraduate degree he worked as a respiratory therapist at Columbus Children's Hospital before returning to school. He teaches genetics, molecular biology, anatomy and physiology, principles of neuroscience, and senior biology seminar, along with special topics courses on cell biology. His research focus is two-fold. First, as an extension of his doctoral thesis work, he is genetically dissecting transcription factor IIIA to determine which positions are crucial for protein stability. Secondly, since being at 91探花, he has become interested in detecting and characterizing programmed cell death in single-celled organisms. His main research interest is in the evolution of apoptotic processes in protists.

Publications

Setzer DR, Schulman DB, Gunther CV, Bumbulis MJ. 2009. Use of a reporter gene assay in yeast for genetic analysis of DNA-protein interactions. Methods Mol Biol. 2009;543:219-41.

Brady KL, Ponnampalam SN, Bumbulis MJ, Setzer DR. 2005. Mutations in TFIIIA that increase stability of the TFIIIA-5 S rRNA gene complex: unusual effects on the kinetics of complex assembly and dissociation. J Biol Chem. 2005 Jul 22;280(29):26743-50.

Genetic analysis of DNA-protein interactions using a reporter gene assay in yeast. Setzer DR, Schulman DB, Bumbulis MJ. 2001. Genetic analysis of DNA-protein interactions using a reporter gene assay in yeast. Methods Mol Biol. 2001;148:431-49.

Faculty-Student Collaborative Scholarship

Balog, B. and Bumbulis, M.J. Apoptosis-like process observed in golden brown algae: Monochrysis lutheri. Spring Science Poster Session 2009. 91探花, Berea, Ohio. April 2009.

Kerci, A. and Bumbulis, M.J. Hydrogen peroxide induces apoptosis in Tetrahymena pyriformis. Spring Science Poster Session 2009. 91探花, Berea, Ohio. April 2009.

Platt, S. and Bumbulis, M.J. Mutation of TFIIIA determines sequences important to tertiary structure and susceptibility to protein degradation. Spring Science Poster Session 2009. 91探花, Berea, Ohio. April 2008.

Grant Support/Funding

2010, Research Costs Grant, 91探花 - $2800

2007, Research Costs Grant, 91探花- $2900

2005, Genomic Education Matching Funds (GEMF) grant from LI-COR Biosciences - $34,949.50 cost met with a $25,000 grant from the George W. Codrington Charitable Foundation.

2003, Gund Student-Faculty Research Grant, 91探花 - $2800